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Source Code:   

import sys      
from PyQt5.QtWidgets import QApplication, QWidget, QCheckBox, QHBoxLayout


class AppDemo(QWidget):
    def __init__(self):
        super().__init__()
        self.resize(400, 200)

        layout = QHBoxLayout()  

        # self.setStyleSheet("""
        #   QCheckBox {
        #       font-size: 50px;
        #   }

        #   QCheckBox::indicator {
        #       width: 40px;
        #       height: 40px;               
        #   }
            

        # """)

        self.checkBoxYes = QCheckBox('Yes') 
        layout.addWidget(self.checkBoxYes)

        self.checkBoxNo = QCheckBox('No')
        layout.addWidget(self.checkBoxNo)

        self.setLayout(layout)
                

if __name__ == '__main__':
    app = QApplication(sys.argv)

    demo = AppDemo()
    demo.show()
    
    try:
        sys.exit(app.exec_())
    except SystemExit:
        print('Closing Window...')